Hayflick在他的“How and Why We Age”一书中说,热量限制可能对人类无效,引用了巴尔的摩老年人纵向研究的数据,该数据表明,瘦身不利于长寿。[需要引用验证] [130]同样有时人们声称,晚年中度肥胖可能会提高生存率,但较新的研究已经发现了混杂因素,如终末期疾病引起的体重减轻。一旦考虑了这些因素,65岁以上的最佳体重对应于较瘦的体重指数23至27。[131]
癌症遗传学家Ronald A. DePinho及其同事发表了对小鼠的研究,其中端粒酶活性首先被遗传去除。然后,在小鼠过早衰老后,它们通过重新激活端粒酶基因来恢复端粒酶活性。结果,小鼠恢复了活力:萎缩的睾丸恢复正常,动物恢复了生育能力。其他器官,如脾脏,肝脏,肠道和大脑,从其退化状态恢复。 “[这一发现]提供了这样一种可能性:通过在已停止工作的细胞中重新唤醒酶,可以减缓正常的人类衰老”,Ronald DePinho说。然而,激活人类端粒酶可能会促进肿瘤的生长。[164]
秀丽隐杆线虫中大多数已知的遗传干预措施使寿命延长1.5至2.5倍。截至2009年,秀丽隐杆线虫的寿命延长记录是单基因突变,使成年人的存活率提高了十倍。[53]模式生物中发现的一些衰老机制的强烈保护意味着它们可能有助于提高人类的生存。但是,好处可能不成比例; C. elegans的寿命增长通常大于果蝇,而果蝇的寿命增长比哺乳动物更大。对此的一种解释是,寿命更长的哺乳动物已经具有许多促进寿命的特征。[53]
另见
Ageing brain
Ageing movement control
Ageing of Europe
Ageing studies
Anti-ageing movement
Biodemography of human longevity
Biogerontology
Biological immortality
Biomarkers of ageing
Clinical geropsychology
Death
Epigenetic clock
Evolution of ageing
Genetics of ageing
Gerontology
Gerascophobia
List of life extension-related topics
Longevity
Mitochondrial theory of ageing
Neuroscience of ageing
Old age
Population ageing
Progeria
Stem cell theory of ageing
Supercentenarian
Transgenerational design
参考
Mortimer RK, Johnston JR (1959). "Life Span of Individual Yeast Cells". Nature. 183 (4677): 1751–1752. Bibcode:1959Natur.183.1751M. doi:10.1038/1831751a0. hdl:2027/mdp.39015078535278. PMID 13666896.
Nutman AP, Bennett VC, Friend CR, Van Kranendonk MJ, Chivas AR (2016). "Rapid emergence of life shown by discovery of 3,700-million-year-old microbial structures". Nature (Submitted manuscript). 537 (7621): 535–38. Bibcode:2016Natur.537..535N. doi:10.1038/nature19355. PMID 27580034.
Rose MR (1991). Evolutionary Biology of Aging. New York: Oxford University Press.
Partridge L, Barton NH (1993). "Optimality, mutation and the evolution of ageing". Nature. 362 (6418): 305–11. Bibcode:1993Natur.362..305P. doi:10.1038/362305a0. PMID 8455716.
Williams, George C. (1957). "leiotropy, Natural Selection, and the Evolution of Senescence". Evolution. 11 (4): 398–411. doi:10.2307/2406060. JSTOR 2406060. Lay summary.
Stewart EJ, Madden R, Paul G, Taddei F (2005). "Aging and death in an organism that reproduces by morphologically symmetric division". PLoS Biology. 3 (2): e45. doi:10.1371/journal.pbio.0030045. PMC 546039. PMID 15685293.
Pereira-Smith OM, Ning Y (1992). "Molecular genetic studies of cellular senescence". Exp Gerontol. 27 (5–6): 519–22. doi:10.1016/0531-5565(92)90006-L. PMID 1426085.
Forster P, Hohoff C, Dunkelmann B, Schürenkamp M, Pfeiffer H, Neuhuber F, Brinkmann B (2015). "Elevated germline mutation rate in teenage fathers". Proc R Soc B. 282 (1803): 1–6. doi:10.1098/rspb.2014.2898. PMC 4345458. PMID 25694621.
Wakayama S, Kohda T, Obokata H, Tokoro M, Li C, Terashita Y, Mizutani E, Nguyen VT, Kishigami S, Ishino F, Wakayama T (2013). "Successful serial recloning in the mouse over multiple generations". Cell Stem Cell. 12 (3): 293–297. doi:10.1016/j.stem.2013.01.005. PMID 23472871.
Stephen Moss (July 2013). "Big ears: they really do grow as we age". The Guardian. MeshID000375; OMIM:502000. Retrieved 9 September 2016.
Gerasimov, I.G.; Ignatov, D.Yu. (2004). "Age Dynamics of Body Mass and Human Lifespan". Journal of Evolutionary Biochemistry and Physiology. 40 (3): 343–349. doi:10.1023/B:JOEY.0000042639.72529.e1.
Rodriguez Valiente A, Trinidad A, Garcia Berrocal JR, Gorriz C, Ramirez Camacho R (April 2014). "Review: Extended high-frequency (9–20 kHz) audiometry reference thresholds in healthy subjects". Int J Audiol. 53 (8): 531–45. doi:10.3109/14992027.2014.893375. PMID 24749665.
Desjardins, Richard; Warnke, Arne Jonas (2012). "Ageing and Skills". OECD Education Working Papers. doi:10.1787/5k9csvw87ckh-en.
Finkel, Deborah; Reynolds, Chandra A. (9 July 2013). Behavior Genetics of Cognition Across the Lifespan. Springer Science & Business Media. ISBN 978-1-4614-7447-0 – via Google Books.
Thurstan SA, Gibbs NK, Langton AK, Griffiths CE, Watson RE, Sherratt MJ (2012). "Chemical consequences of cutaneous photoageing". Chem Cent J. 6 (1): 34. doi:10.1186/1752-153X-6-34. PMC 3410765. PMID 22534143.
pmhdev (25 March 2015). "Infertility: Overview". Institute for Quality and Efficiency in Health Care (IQWiG) – via www.ncbi.nlm.nih.gov.
"Facts About Presbyopia". Last Reviewed October 2010: National Eye Institute. Retrieved 11 September 2016.
Weale RA (2003). "Epidemiology of refractive errors and presbyopia". Surv Ophthalmol. 48 (5): 515–43. doi:10.1016/S0039-6257(03)00086-9. PMID 14499819.
Truscott RJ (2009). "resbyopia. Emerging from a blur towards an understanding of the molecular basis for this most common eye condition". Exp Eye Res. 88 (2): 241–47. doi:10.1016/j.exer.2008.07.003. PMID 18675268.
Pathai, S; Shiels, PG; Lawn, SD; Cook, C; Gilbert, C (March 2013). "The eye as a model of ageing in translational research – molecular, epigenetic and clinical aspects". Ageing Research Reviews. 12 (2): 490–508. doi:10.1016/j.arr.2012.11.002. PMID 23274270.
Pandhi, D; Khanna, D (2013). "remature graying of hair". Indian Journal of Dermatology, Venereology and Leprology. 79 (5): 641–53. doi:10.4103/0378-6323.116733. PMID 23974581.
Hamilton, J. B. (1 March 1951). "atterned loss of hair in man; types and incidence". Annals of the New York Academy of Sciences. 53 (3): 708–28. Bibcode:1951NYASA..53..708H. doi:10.1111/j.1749-6632.1951.tb31971.x. PMID 14819896.
Vary JC, Jr (November 2015). "Selected Disorders of Skin Appendages – Acne, Alopecia, Hyperhidrosis". The Medical Clinics of North America. 99 (6): 1195–211. doi:10.1016/j.mcna.2015.07.003. PMID 26476248.
Takahashi, TA; Johnson, KM (May 2015). "Menopause". The Medical Clinics of North America. 99 (3): 521–34. doi:10.1016/j.mcna.2015.01.006. PMID 25841598.
Thomas, Elaine; Peat, George; Croft, Peter (2014). "Defining and mapping the person with osteoarthritis for population studies and public health". Rheumatology (Oxford). 53 (2): 338–45. doi:10.1093/rheumatology/ket346. PMC 3894672. PMID 24173433.
"Hearing Loss and Older Adults" (Last Updated June 3, 2016). National Institute on Deafness and Other Communication Disorders. 26 January 2016. Retrieved 11 September 2016.
Rubel, Edwin W.; Furrer, Stephanie A.; Stone, Jennifer S. (2013). "Review: A brief history of hair cell regeneration research and speculations on the future". Hearing Research. 297: 42–51. doi:10.1016/j.heares.2012.12.014. PMC 3657556. PMID 23321648.
"Facts About Cataract". September 2015. Retrieved 14 August 2016.
Fried, LP; Tangen, CM; Walston, J; Newman, AB; Hirsch, C; Gottdiener, J; Seeman, T; Tracy, R; Kop, WJ; Burke, G; McBurnie, MA (March 2001). "Frailty in older adults: evidence for a phenotype". The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 56 (3): M146–56. CiteSeerX 10.1.1.456.139. doi:10.1093/gerona/56.3.m146. PMID 11253156.
Percentage derived from Table 2 in Fried et al. 2001
Wang JC, Bennett M (2012). "Aging and atherosclerosis: mechanisms, functional consequences, and potential therapeutics for cellular senescence". Circ Res. 111 (2): 245–59. doi:10.1161/CIRCRESAHA.111.261388. PMID 22773427.
Herrington W, Lacey B, Sherliker P, Armitage J, Lewington S (2016). "Epidemiology of Atherosclerosis and the Potential to Reduce the Global Burden of Atherothrombotic Disease". Circ Res. 118 (4): 535–46. doi:10.1161/CIRCRESAHA.115.307611. PMID 26892956.
{https://laysamagazine.com/pdf/heart-disease-stroke-statistics/}
"Does Human Life Span Really Have a Limit?". WebMD. 28 June 2018.
Zimmer, Carl (5 October 2016). "What's the Longest Humans Can Live? 115 Years, New Study Says". The New York Times. Retrieved 6 October 2016.
Dong, Xiao; Milholland, Brandon; Vijg, Jan (5 October 2016). "Evidence for a limit to human lifespan". Nature. 538 (7624): 257–59. Bibcode:2016Natur.538..257D. doi:10.1038/nature19793. PMID 27706136.
Larson, EB; Yaffe, K; Langa, KM (12 December 2013). "New insights into the dementia epidemic". The New England Journal of Medicine. 369 (24): 2275–77. doi:10.1056/nejmp1311405. PMC 4130738. PMID 24283198.
Umphred, Darcy (2012). Neurological rehabilitation (6th ed.). St. Louis, MO: Elsevier Mosby. p. 838. ISBN 978-0-323-07586-2.
Schaie, K. Warner (2005). Developmental Influences on Adult Intelligence. doi:10.1093/acprofso/9780195156737.001.0001. ISBN 978-0-19-515673-7.[page needed]
Stuart-Hamilton, Ian (2006). The Psychology of Ageing: An Introduction. London: Jessica Kingsley Publishers. ISBN 978-1-84310-426-1.
Marner, Lisbeth; Nyengaard, Jens R.; Tang, Yong; Pakkenberg, Bente (2003). "Marked loss of myelinated nerve fibers in the human brain with age". The Journal of Comparative Neurology. 462 (2): 144–52. doi:10.1002/cne.10714. PMID 12794739.
Peters, Alan (1 January 2007). "The Effects of Normal Aging on Nerve Fibers and Neuroglia in the Central Nervous System". In Riddle, David R. (ed.). Brain Aging: Models, Methods, and Mechanisms. Frontiers in Neuroscience. CRC Press/Taylor & Francis. ISBN 978-0-8493-3818-2. PMID 21204349.
Worrall, L. & Hickson, L.M. (2003). "Theoretical foundations of communication disability in aging", pp. 32–33 in Linda E. Worrall & Louise M. Hickson(Eds.). Communication disability in aging: from prevention to intervention. Clifton Park, NY: Delmar Learning
Lys, R.; Belanger, E.; Phillips, S.P. (April 2019). "Improved mood despite worsening physical health in older adults: Findings from the International Mobility in Aging Study (IMIAS)". PLOS ONE. 14. doi:10.1371/journal.pone.0214988. PMID 30958861.
Mehta, S (September 2015). "Age-Related Macular Degeneration". Primary Care. 42 (3): 377–91. doi:10.1016/j.pop.2015.05.009. PMID 26319344.
Nussbaum, J.F., Thompson, T.L., & Robinson, J.D. (1989). "Barriers to conversation", pp. 234–53 in Jon F. Nussbaum, Teresa Thompson, James D. Robinson (Eds.). Communication and aging. New York: Harper & Row
Belikov, Aleksey V. (January 2019). "Age-related diseases as vicious cycles". Ageing Research Reviews. 49: 11–26. doi:10.1016/j.arr.2018.11.002. PMID 30458244.
De Grey, Aubrey D.N.J (2007). "Life Span Extension Research and Public Debate: Societal Considerations". Studies in Ethics, Law, and Technology. 1. CiteSeerX 10.1.1.395.745. doi:10.2202/1941-6008.1011.
Lopez, Alan D; Mathers, Colin D; Ezzati, Majid; Jamison, Dean T; Murray, Christopher JL (2006). "Global and regional burden of disease and risk factors, 2001: Systematic analysis of population health data". The Lancet. 367 (9524): 1747–57. doi:10.1016/S0140-6736(06)68770-9. PMID 16731270.
Brunet Lab: Molecular Mechanisms of Longevity and Age Related Diseases. Stanford.edu. Retrieved on 11 April 2012.
Janssens GE, Meinema AC, González J, Wolters JC, Schmidt A, Guryev V, Bischoff R, Wit EC, Veenhoff LM, Heinemann M (2015). "rotein biogenesis machinery is a driver of replicative aging in yeast". eLife. 4: e08527. doi:10.7554/eLife.08527. PMC 4718733. PMID 26422514.
Deepti S. Wilkinson; Rebecca C. Taylor; Andrew Dillin (2012). "Analysis of Aging in Caenorhabditis elegans". In Joel H. Rothman; Andrew Singson (eds.). Caenorhabditis Elegans: Cell Biology and Physiology. Academic Press. pp. 353–81. ISBN 978-0-12-394620-1.
Shmookler Reis RJ, Bharill P, Tazearslan C, Ayyadevara S (2009). "Extreme-longevity mutations orchestrate silencing of multiple signaling pathways". Biochim Biophys Acta. 1790 (10): 1075–83. doi:10.1016/j.bbagen.2009.05.011. PMC 2885961. PMID 19465083.
"Mitochondrial Theory of Aging and Other Aging Theories". 1Vigor. Retrieved 4 October 2013.
Jin, Kunlin (2010). "Modern Biological Theories of Aging". Aging Dis. 1 (2): 72–74. PMC 2995895. PMID 21132086.
Lopez-Otin, C; Blasco, MA; Partridge, L; Serrano, M; Kroemer, G (2013). "The hallmarks of aging". Cell. 153 (6): 1194–217. doi:10.1016/j.cell.2013.05.039. PMC 3836174. PMID 23746838.
Guarente, Leonard P.; Partridge, Linda; Wallace, Douglas C. (2008). Molecular Biology of Aging. New York: Cold Spring Harbor. pp. 347–62. ISBN 978-0-87969-824-9.
Taylor RC, Dillin A (2011). "Aging as an event of proteostasis collapse". Cold Spring Harb Perspect Biol. 3 (5): a004440. doi:10.1101/cshperspect.a004440. PMC 3101847. PMID 21441594.
Melzer, S; Lens, F; Gennen, J; Vanneste, S; Rohde, A; Beeckman, T (2008). "Flowering-time genes modulate meristem determinacy and growth form in Arabidopsis thaliana". Nature Genetics. 40 (12): 1489–92. doi:10.1038/ng.253. PMID 18997783.
Chesterton, Marnie (12 June 2017). "The oldest living thing on Earth". BBC News. Retrieved 16 September 2017.
"Oldlist". Rocky Mountain Tree Ring Research. Retrieved 12 August 2016.
Danuta Sosnowska; Chris Richardson; William E. Sonntag; Anna Csiszar; Zoltan Ungvari; Iain Ridgway (2014). "A Heart That Beats for 500 Years: Age-Related Changes in Cardiac Proteasome Activity, Oxidative Protein Damage and Expression of Heat Shock Proteins, Inflammatory Factors, and Mitochondrial Complexes in Arctica islandica, the Longest-Living Noncolonial Animal". J Gerontol A Biol Sci Med Sci. 69 (12): 1448–61. doi:10.1093/gerona/glt201. PMC 4271020. PMID 24347613.
Julius Nielsen; Rasmus B. Hedeholm; Jan Heinemeier; Peter G. Bushnell; Jørgen S. Christiansen; Jesper Olsen; Christopher Bronk Ramsey; Richard W. Brill; Malene Simon; Kirstine F. Steffensen; John F. Steffensen (2016). "Eye lens radiocarbon reveals centuries of longevity in the Greenland shark (Somniosus microcephalus)". Science. 353 (6300): 702–704. Bibcode:2016Sci...353..702N. doi:10.1126/science.aaf1703. PMID 27516602.
Durkin, A.; Fisher, C.R.; Cordes, E.E. (2017). "Extreme longevity in a deep-sea vestimentiferan tubeworm and its implications for the evolution of life history strategies". The Science of Nature. 104 (7–8): 63. Bibcode:2017SciNa.104...63D. doi:10.1007/s00114-017-1479-z. PMID 28689349.
Timiras, Paola S. (2003) Physiological Basis of Ageing and Geriatrics. Informa Health Care. ISBN 0-8493-0948-4. p. 26.
Silverman, Jacob (5 July 2007). "Is there a 400 pound lobster out there?". howstuffworks.
Wallace, David Foster (2005). Consider the Lobster and Other Essays. Little, Brown & Company. ISBN 978-0-316-15611-0.[page needed]
Guerin, J (2004). "Emerging area of aging research: long-lived animals with "negligible senescence"". Ann N Y Acad Sci. 1019 (1): 518–20. Bibcode:2004NYASA1019..518G. doi:10.1196/annals.1297.096. PMID 15247078.
Bartke A (2011). "Single-gene mutations and healthy ageing in mammals". Philos Trans R Soc Lond B Biol Sci. 366 (1561): 28–34. doi:10.1098/rstb.2010.0281. PMC 3001310. PMID 21115527.
"What 3 Things Can I Do to Extend the Length of My Life?". Time. Retrieved 15 November 2018.
Berdyshev, G; Korotaev, G; Boiarskikh, G; Vaniushin, B (1967). "Nucleotide composition of DNA and RNA from somatic tissues of humpback and its changes during spawning". Biokhimiia. 31: 88–993.
Marioni, R; Shah, S; McRae, A; Chen, B; Colicino, E; Harris, S; Gibson, J; Henders, A; Redmond, P; Cox, S; Pattie, A; Corley, J; Murphy, L; Martin, N; Montgomery, G; Feinberg, A; Fallin, M; Multhaup, M; Jaffe, A; Joehanes, R; Schwartz, J; Just, A; Lunetta, K; Murabito, JM; Starr, J; Horvath, S; Baccarelli, A; Levy, D; Visscher, P; Wray, N; Deary, I (2015). "DNA methylation age of blood predicts all-cause mortality in later life". Genome Biology. 16 (1): 25. doi:10.1186/s13059-015-0584-6. PMC 4350614. PMID 25633388.
Christiansen, L (2015). "DNA methylation age is associated with mortality in a longitudinal Danish twin study". Aging Cell. 15 (1): 149–54. doi:10.1111/acel.12421. PMC 4717264. PMID 26594032.
Horvath, S (2015). "Decreased epigenetic age of PBMCs from Italian semi-supercentenarians and their offspring". Aging (Dec).
Ocampo, A.; et al. (2016). "In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming". Cell. 167 (7): 1719–33. doi:10.1016/j.cell.2016.11.052. PMC 5679279. PMID 27984723.
Tina Hesman Saey (15 December 2016). "roteins that reprogram cells can turn back mice's aging clock". Retrieved 19 December 2016.
Callaway, Ewen (2016). "Destroying worn-out cells makes mice live longer". Nature. doi:10.1038/nature.2016.19287. Retrieved 25 May 2019.
Hall, Brandon M.; Balan, Vitaly; Gleiberman, Anatoli S.; Strom, Evguenia; Krasnov, Peter; Virtuoso, Lauren P.; Rydkina, Elena; Vujcic, Slavoljub; Balan, Karina; Gitlin, Ilya; Leonova, Katerina; Polinsky, Alexander; Chernova, Olga B.; Gudkov, Andrei V. (2016). "Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells". doi:10.18632/aging.100991. Retrieved 25 May 2019.
"Great Results". oisinbio.com. Retrieved 25 May 2019. Oisín has shown as much as an 80% reduction in senescent cells in cell culture and significant reductions of senescent cell burden in naturally aged mice.
Willcox B.J. (2008). "FOXO3A genotype is strongly associated with human longevity". PNAS. 105 (37): 13987–92. Bibcode:2008PNAS..10513987W. doi:10.1073/pnas.0801030105. PMC 2544566. PMID 18765803.
Flachsbart F, Caliebe A, Kleindorp R, Blanché H, von Eller-Eberstein H, Nikolaus S, Schreiber S, Nebel A (2009). "Association of FOXO3A variation with human longevity confirmed in German centenarians". PNAS. 106 (8): 2700–05. Bibcode:2009PNAS..106.2700F. doi:10.1073/pnas.0809594106. PMC 2650329. PMID 19196970.
Ghosh, H. S.; McBurney, M; Robbins, P. D. (2010). "SIRT1 Negatively Regulates the Mammalian Target of Rapamycin". PLoS ONE. 5 (2): e9199. Bibcode:2010PLoSO...5.9199G. doi:10.1371/journal.pone.0009199. PMC 2821410. PMID 20169165.
Fontana L, Partridge L, Longo VD (2010). "Extending healthy life span—from yeast to humans". Science. 328 (5976): 321–26. Bibcode:2010Sci...328..321F. doi:10.1126/science.1172539. PMC 3607354. PMID 20395504.
Johnson, Simon C.; Rabinovitch, Peter S.; Kaeberlein, Matt (2013). "MTOR is a key modulator of ageing and age-related disease". Nature. 493 (7432): 338–45. Bibcode:2013Natur.493..338J. doi:10.1038/nature11861. PMC 3687363. PMID 23325216.
Halicka HD, Zhao H, Li J, Lee YS, Hsieh TC, Wu JM, Darzynkiewicz Z. (2012) Potential anti-aging agents suppress the level of constitutive mTOR- and DNA damage- signaling. Aging (Albany NY). 2012 Dec;4(12):952-65. PMID 23363784, PMC 3615161.
Junnila, RK; List, EO; Berryman, DE; Murrey, JW; Kopchick, JJ (2013). "The GH/IGF-1 axis in ageing and longevity". Nat Rev Endocrinol. 9 (6): 366–76. doi:10.1038/nrendo.2013.67. PMC 4074016. PMID 23591370.
J Sun; Kale, SP; Childress, AM; Pinswasdi, C; Jazwinski, SM (15 July 1994). "Divergent roles of RAS1 and RAS2 in yeast longevity". Journal of Biological Chemistry. 269 (28): 18638–45. PMID 8034612.
Wei M, Fabrizio P, Hu J, Ge H, Cheng C, Li L, Longo VD (2008). "Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9". PLoS Genet. 4 (1): 139–149. doi:10.1371/journal.pgen.0040013. PMC 2213705. PMID 18225956.
"10-Fold Life Span Extension Reported". University of Southern California. Archived from the original on 4 March 2016. Retrieved 7 January 2016.
Stibich, Mark (19 April 2009) Telomere Shortening – The Secret to Aging?. About.com
m. Mikhelson, Victor; Gamaley, Irina (2013). "Telomere Shortening is a Sole Mechanism of Aging in Mammals". Current Aging Science. 5 (3): 203–08. doi:10.2174/1874609811205030006. PMID 23387887.
Hayflick, L. (1987) Origins of longevity. In Warner, H.R., Butler, R.N., Sprott, R.L. and Schneider, E.L. (eds), Modern Biological Theories of Aging. Raven Press, New York, pp. 21–34. ISBN 0-88167-310-2
Bernstein C, Bernstein H. (1991) Aging, Sex, and DNA Repair. Academic Press, San Diego. ISBN 0-12-092860-4. pp. 314, 320, 326
Hemann, M T.; Greider, CW (2000). "Wild-derived inbred mouse strains have short telomeres". Nucleic Acids Research. 28 (22): 4474–78. doi:10.1093/nar/28.22.4474. PMC 113886. PMID 11071935.
Blasco, María A; Lee, Han-Woong; Hande, M. Prakash; Samper, Enrique; Lansdorp, Peter M; Depinho, Ronald A; Greider, Carol W (1997). "Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA". Cell. 91 (1): 25–34. doi:10.1016/S0092-8674(01)80006-4. PMID 9335332.
Kipling, David; Cooke, Howard J. (1990). "Hypervariable ultra-long telomeres in mice". Nature. 347 (6291): 400–02. Bibcode:1990Natur.347..400K. doi:10.1038/347400a0. PMID 2170845.
Nordfjäll, K; Svenson, U; Norrback, K. F.; Adolfsson, R; Lenner, P; Roos, G (2009). "The Individual Blood Cell Telomere Attrition Rate is Telomere Length Dependent". PLoS Genetics. 5 (2): e1000375. doi:10.1371/journal.pgen.1000375. PMC 2633043. PMID 19214207.
Nyström, T. (2003). "The free-radical hypothesis of aging goes prokaryotic". Cellular and Molecular Life Sciences. 60 (7): 1333–41. doi:10.1007/s00018-003-2310-X. PMID 12943222.
Kang, H.-J.; Feng, Z.; Sun, Y.; Atwal, G.; Murphy, M. E.; Rebbeck, T. R.; Rosenwaks, Z.; Levine, A. J.; Hu, W. (2009). "Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans". Proceedings of the National Academy of Sciences. 106 (24): 9761–66. Bibcode:2009PNAS..106.9761K. doi:10.1073/pnas.0904280106. PMC 2700980. PMID 19470478.
Smith, K.R.; Hanson, H.A.; Mineau, G.P.; Buys, S.S. (2011). "Effects of BRCA1 and BRCA2 mutations on female fertility". Proceedings of the Royal Society B: Biological Sciences. 279 (1732): 1389–95. doi:10.1098/rspb.2011.1697. PMC 3282366. PMID 21993507.
Bowen, Richard L.; Atwood, Craig S. (2004). "Living and Dying for Sex". Gerontology. 50 (5): 265–90. doi:10.1159/000079125. PMID 15331856.
Atwood, Craig S.; Bowen, Richard L. (2011). "The reproductive-cell cycle theory of aging: An update". Experimental Gerontology. 46 (2–3): 100–07. doi:10.1016/j.exger.2010.09.007. PMID 20851172.
Mair W, Steffen KK, Dillin A (2011). "SIP-ing the elixir of youth". Cell. 146 (6): 859–60. doi:10.1016/j.cell.2011.08.026. PMID 21925309.
Galindo, Yadira (26 December 2018). "UC San Diego Researchers Identify How Skin Ages, Loses Fat and Immunity" (Press release). University of California San Diego.
Zhang, Ling-juan & 13 co-authors (26 December 2018). "Age-Related Loss of Innate Immune Antimicrobial Function Of Dermal Fat Is Mediated By Transforming Growth Factor Beta". Immunity.
Gensler, Helen L.; Bernstein, Harris (1981). "DNA Damage as the Primary Cause of Aging". The Quarterly Review of Biology. 56 (3): 279–303. doi:10.1086/412317. JSTOR 2826464. PMID 7031747.
Sinha, Jitendra Kumar; Ghosh, Shampa; Swain, Umakanta; Giridharan, Nappan Veethil; Raghunath, Manchala (2014). "Increased macromolecular damage due to oxidative stress in the neocortex and hippocampus of WNIN/Ob, a novel rat model of premature aging". Neuroscience. 269: 256–64. doi:10.1016/j.neuroscience.2014.03.040. PMID 24709042.
Freitas, Alex A.; De Magalhães, João Pedro (2011). "A review and appraisal of the DNA damage theory of ageing". Mutation Research/Reviews in Mutation Research. 728 (1–2): 12–22. doi:10.1016/j.mrrev.2011.05.001. PMID 21600302.
L. Robert; J. Labat-Robert; A. M. Robert (2010). "Genetic, epigenetic and posttranslational mechanisms of aging". Biogerontology. 11 (4): 387–99. doi:10.1007/s10522-010-9262-y. PMID 20157779.
Strehler, Bernard L. (1986). "Genetic instability as the primary cause of human aging". Experimental Gerontology. 21 (4–5): 283–319. doi:10.1016/0531-5565(86)90038-0. PMID 3545872.
Gavrilov, L. A.; Gavrilova, N. S. (2006), "Reliability Theory of Aging and Longevity", pp. 3–42 in Handbook of the Biology of Aging, ed. Masoro E. J. and Austad S. N, Academic Press, San Diego, CA.
Carroll B, Hewitt G, Korolchuk VI (2013). "Autophagy and ageing: implications for age-related neurodegenerative diseases". Essays Biochem. 55: 119–31. doi:10.1042/bse0550119. PMID 24070476.
Cui M, Yu H, Wang J, Gao J, Li J (2013). "Chronic Caloric Restriction and Exercise Improve Metabolic Conditions of Dietary-Induced Obese Mice in Autophagy Correlated Manner without Involving AMPK". J Diabetes Res. 2013: 1–8. doi:10.1155/2013/852754. PMC 3671310. PMID 23762877.
Jin K (2010). "Modern Biological Theories of Aging". Aging Dis. 1 (2): 72–74. PMC 2995895. PMID 21132086.
Bjorksten, Johan; Tenhu, Heikki (1990). "The crosslinking theory of aging — Added evidence". Experimental Gerontology. 25 (2): 91–95. doi:10.1016/0531-5565(90)90039-5. PMID 2115005.
Trifunovic, A.; Larsson, N.-G. (1 February 2008). "Mitochondrial dysfunction as a cause of ageing". Journal of Internal Medicine. 263 (2): 167–78. doi:10.1111/j.1365-2796.2007.01905.x. ISSN 1365-2796. PMID 18226094.
Harman, D. (1981). "The aging process". Proceedings of the National Academy of Sciences. 78 (11): 7124–28. Bibcode:1981PNAS...78.7124H. doi:10.1073/pnas.78.11.7124. PMC 349208. PMID 6947277.
Schulz, Tim J.; Zarse, Kim; Voigt, Anja; Urban, Nadine; Birringer, Marc; Ristow, Michael (2007). "Glucose Restriction Extends Caenorhabditis elegans Life Span by Inducing Mitochondrial Respiration and Increasing Oxidative Stress". Cell Metabolism. 6 (4): 280–93. doi:10.1016/j.cmet.2007.08.011. PMID 17908557.
Hamilton ML, Van Remmen H, Drake JA, Yang H, Guo ZM, Kewitt K, Walter CA, Richardson A (2001). "Does oxidative damage to DNA increase with age?". Proc. Natl. Acad. Sci. U.S.A. 98 (18): 10469–74. Bibcode:2001PNAS...9810469H. doi:10.1073/pnas.171202698. PMC 56984. PMID 11517304.
Wolf FI, Fasanella S, Tedesco B, Cavallini G, Donati A, Bergamini E, Cittadini A (2005). "eripheral lymphocyte 8-OHdG levels correlate with age-associated increase of tissue oxidative DNA damage in Sprague-Dawley rats. Protective effects of caloric restriction". Exp. Gerontol. 40 (3): 181–88. doi:10.1016/j.exger.2004.11.002. PMID 15763395.
Anson, R. M.; Bohr, V. A. (October 2000). "Mitochondria, oxidative DNA damage, and aging". Journal of the American Aging Association. 23 (4): 199–218. doi:10.1007/s11357-000-0020-y. ISSN 2152-4041. PMC 3455271. PMID 23604866.
Guarente L, Picard F (2005). "Calorie restriction—the SIR2 connection". Cell. 120 (4): 473–82. doi:10.1016/j.cell.2005.01.029. PMID 15734680.
Agarwal B, Baur JA (2011). "Resveratrol and life extension". Ann N Y Acad Sci. 1215 (1): 138–43. Bibcode:2011NYASA1215..138A. doi:10.1111/j.1749-6632.2010.05850.x. PMID 21261652.
Larson-Meyer DE; et al. (2008). "Effect of 6-month calorie restriction and exercise on serum and liver lipids and markers of liver function". Obesity (Silver Spring). 16 (6): 1355–62. doi:10.1038/oby.2008.201. PMC 2748341. PMID 18421281.
Heilbronn LK; et al. (2006). "Effect of 6-month calorie restriction on biomarkers of longevity, metabolic adaptation, and oxidative stress in overweight individuals: a randomized controlled trial". JAMA. 295 (13): 1539–48. doi:10.1001/jama.295.13.1539. PMC 2692623. PMID 16595757.
Colman RJ, Anderson RM, Johnson SC, Kastman EK, et al. (2009). "Caloric restriction delays disease onset and mortality in rhesus monkeys". Science. 325 (5937): 201–04. Bibcode:2009Sci...325..201C. doi:10.1126/science.1173635. PMC 2812811. PMID 19590001.
Mattison, Julie A.; et al. (2012). "Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study". Nature. 489 (7415): 318–321. Bibcode:2012Natur.489..318M. doi:10.1038/nature11432. PMC 3832985. PMID 22932268.
Colman RJ; Beasley TM; Kemnitz JW; Johnson SC; Weindruch R; Anderson RM (1 April 2014). "Caloric restriction reduces age-related and all-cause mortality in rhesus monkeys". Nature Communications. 5: 3557. Bibcode:2014NatCo...5E3557C. doi:10.1038/ncomms4557. PMC 3988801. PMID 24691430.
"There may be little advantage of moderate CR over modest CR—this would be an extremely important discovery and one that merits further investigation."
Hayflick, Leonard. (1994). How and why we age. New York: Ballantine Books. p. 261. ISBN 978-0-345-33918-8. OCLC 29908633.
Bowman K; Delgado J; Henley WE; Masoli JA; Kos K; Brayne C; Thokala P; Lafortune L; Kuchel GA; Ble A; Melzer D; Ageing Well Programme of the NIHR School for Public Health Research, England (4 August 2016). "Obesity in Older People With and Without Conditions Associated With Weight Loss: Follow-up of 955,000 Primary Care Patients". J Gerontol A Biol Sci Med Sci. 72 (2): 203–09. doi:10.1093/gerona/glw147. PMC 5233914. PMID 27492450.
Nakagawa, Shinichi; Lagisz, Malgorzata; Hector, Katie L.; Spencer, Hamish G. (1 June 2012). "Comparative and meta-analytic insights into life extension via dietary restriction". Aging Cell. 11 (3): 401–09. doi:10.1111/j.1474-9726.2012.00798.x. ISSN 1474-9726. PMID 22268691.
Simpson, Stephen J.; Raubenheimer, David (22 October 2009). "Macronutrient balance and lifespan". Aging. 1 (10): 875–80. doi:10.18632/aging.100098. ISSN 1945-4589. PMC 2815731. PMID 20157561.
Melnik, Bodo C. (15 March 2012). "Leucine signaling in the pathogenesis of type 2 diabetes and obesity". World Journal of Diabetes. 3 (3): 38–53. doi:10.4239/wjd.v3.i3.38. ISSN 1948-9358. PMC 3310004. PMID 22442749.
Yan, Lijun; Lamb, Richard F. (1 August 2012). "Amino acid sensing and regulation of mTORC1". Seminars in Cell & Developmental Biology. 23 (6): 621–25. doi:10.1016/j.semcdb.2012.02.001. ISSN 1096-3634. PMID 22342805.
Rees, Karen; Takeda, Andrea; Martin, Nicole; Ellis, Leila; Wijesekara, Dilini; Vepa, Abhinav; Das, Archik; Hartley, Louise; Stranges, Saverio (13 March 2019). Cochrane Heart Group (ed.). "Mediterranean-style diet for the primary and secondary prevention of cardiovascular disease". Cochrane Database of Systematic Reviews. doi:10.1002/14651858.CD009825.pub3.
Sofi F, Cesari F, Abbate R, Gensini GF, Casini A (2008). "Adherence to Mediterranean diet and health status: meta-analysis". BMJ (Clinical Research Ed.). 337 (sep11 2): a1344. doi:10.1136/bmj.a1344. PMC 2533524. PMID 18786971.
de Gaetano, Giovanni (29 August 2016). "Mediterranean diet associated with lower risk of early death in cardiovascular disease patients. European Society of Cardiology". ScienceDaily.
Rhonda Rowland (15 February 2002). "Experts challenge study linking sleep, life span". CNN. Retrieved 29 October 2013.
Patel SR, Ayas NT, Malhotra MR, White DP, Schernhammer ES, Speizer FE, Stampfer MJ, Hu FB (May 2004). "A prospective study of sleep duration and mortality risk in women". Sleep. 27 (3): 440–44. doi:10.1093/sleep/27.3.440. PMID 15164896.
Ferrie JE, Shipley MJ, Cappuccio FP, Brunner E, Miller MA, Kumari M, Marmot MG (December 2007). "A prospective study of change in sleep duration: associations with mortality in the Whitehall II cohort". Sleep. 30 (12): 1659–66. doi:10.1093/sleep/30.12.1659. PMC 2276139. PMID 18246975. Lay summary – University of Warwick.
Patel SR, Malhotra A, Gottlieb DJ, White DP, Hu FB (July 2006). "Correlates of long sleep duration". Sleep. 29 (7): 881–9. doi:10.1093/sleep/29.7.881. PMC 3500381. PMID 16895254.; cf. Irwin MR, Ziegler M (February 2005). "Sleep deprivation potentiates activation of cardiovascular and catecholamine responses in abstinent alcoholics". Hypertension. 45 (2): 252–57. doi:10.1161/01.HYP.0000153517.44295.07. PMID 15642774.
Yetish G, Kaplan H, Gurven M, Wood B, Pontzer H, Manger PR, Wilson C, McGregor R, Siegel JM (November 2015). "Natural sleep and its seasonal variations in three pre-industrial societies". Curr. Biol. 25 (21): 2862–68. doi:10.1016/j.cub.2015.09.046. PMC 4720388. PMID 26480842.
Gremeaux, V; Gayda, M; Lepers, R; Sosner, P; Juneau, M; Nigam, A (December 2012). "Exercise and longevity". Maturitas. 73 (4): 312–17. doi:10.1016/j.maturitas.2012.09.012. PMID 23063021.
Department Of Health And Human Services, United States (1996). Physical Activity and Health. United States Department of Health. ISBN 978-1-4289-2794-0.
Woods, Jeffrey A.; Wilund, Kenneth R.; Martin, Stephen A.; Kistler, Brandon M. (29 October 2011). "Exercise, Inflammation and Aging". Aging and Disease. 3 (1): 130–40. ISSN 2152-5250. PMC 3320801. PMID 22500274.
Kyu, Hmwe H; Bachman, Victoria F; Alexander, Lily T; Mumford, John Everett; Afshin, Ashkan; Estep, Kara; Veerman, J Lennert; Delwiche, Kristen; Iannarone, Marissa L; Moyer, Madeline L; Cercy, Kelly; Vos, Theo; Murray, Christopher J L; Forouzanfar, Mohammad H (9 August 2016). "hysical activity and risk of breast cancer, colon cancer, diabetes, ischemic heart disease, and ischemic stroke events: systematic review and dose-response meta-analysis for the Global Burden of Disease Study 2013". BMJ. 354: i3857. doi:10.1136/bmj.i3857. PMC 4979358. PMID 27510511.
Notterman DA, Mitchell C (2015). "Epigenetics and Understanding the Impact of Social Determinants of Health". Pediatric Clinics of North America (Review). 62 (5): 1227–40. doi:10.1016/j.pcl.2015.05.012. PMC 4555996. PMID 26318949.
Quinlan J, Tu MT, Langlois EV, Kapoor M, Ziegler D, Fahmi H, Zunzunegui MV (2014). "rotocol for a systematic review of the association between chronic stress during the life course and telomere length". Syst Rev (Review). 3 (40): 40. doi:10.1186/2046-4053-3-40. PMC 4022427. PMID 24886862.
Noordam R, Gunn DA, Tomlin CC, Rozing MP, Maier AB, Slagboom PE, Westendorp RG, van Heemst D, de Craen AJ, Leiden Longevity Study group (2012). "Cortisol serum levels in familial longevity and perceived age: the Leiden longevity study". Psychoneuroendocrinology. 37 (10): 1669–75. doi:10.1016/j.psyneuen.2012.02.013. PMID 22429748.
Lazzarino AI, Hamer M, Gaze D, Collinson P, Steptoe A (2013). "The association between cortisol response to mental stress and high-sensitivity cardiac troponin T plasma concentration in healthy adults". J Am Coll Cardiol. 62 (18): 1694–1701. doi:10.1016/j.jacc.2013.05.070. PMC 3807660. PMID 23810896.
Holt-Lunstad J, Smith TB, Layton JB (2010). "Social Relationships and Mortality Risk: A Meta-analytic Review". PLOS Medicine. 7 (7): e1000316. doi:10.1371/journal.pmed.1000316. PMC 2910600. PMID 20668659.
"Social ties are good for your health". stanford.edu. Archived from the original on 11 September 2016.
Koenig H.G., King D.E., Carson V.B (2012). Handbook of religion and health (2nd ed.). New York: Oxford University Press. p476
"Married Vs Single: What Science Says Is Better For Your Health". medicaldaily.com. 2 April 2015.
Shor E, Roelfs DJ, Bugyi P, Schwartz JE (2012). "Meta-analysis of marital dissolution and mortality: reevaluating the intersection of gender and age". Soc Sci Med. 75 (1): 46–59. doi:10.1016/j.socscimed.2012.03.010. PMC 3881174. PMID 22534377.
Lam YY, Peterson CM, Ravussin E (2013). "Resveratrol vs. calorie restriction: data from rodents to humans". Exp Gerontol. 48 (10): 1018–24. doi:10.1016/j.exger.2013.04.005. PMID 23624181.
Pryor, R; Cabreiro, F (1 November 2015). "Repurposing metformin: an old drug with new tricks in its binding pockets". The Biochemical Journal. 471 (3): 307–22. doi:10.1042/bj20150497. PMC 4613459. PMID 26475449.
Powers RW, Kaeberlein M, Caldwell SD, Kennedy BK, Fields S (2006). "Extension of chronological life span in yeast by decreased TOR pathway signaling". Genes Dev. 20 (2): 174–84. doi:10.1101/gad.1381406. PMC 1356109. PMID 16418483.
Harrison DE, Strong R, Sharp ZD, Nelson JF, Astle CM, Flurkey K, Nadon NL, Wilkinson JE, Frenkel K, Carter CS, Pahor M, Javors MA, Fernandez E, Miller RA (2009). "Rapamycin fed late in life extends lifespan in genetically heterogeneous mice". Nature. 460 (7253): 392–95. Bibcode:2009Natur.460..392H. doi:10.1038/nature08221. PMC 2786175. PMID 19587680. Lay summary – The Times (8 July 2009).
Miller RA, Harrison DE, Astle CM, Baur JA, Boyd AR, de Cabo R, Fernandez E, Flurkey K, Javors MA, Nelson JF, Orihuela CJ, Pletcher S, Sharp ZD, Sinclair D, Starnes JW, Wilkinson JE, Nadon NL, Strong R (February 2011). "Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice". J. Gerontol. A Biol. Sci. Med. Sci. 66 (2): 191–201. doi:10.1093/gerona/glq178. PMC 3021372. PMID 20974732.
Ingram DK, Roth GS (March 2011). "Glycolytic inhibition as a strategy for developing calorie restriction mimetics". Experimental Gerontology (review). 46 (2–3): 148–54. doi:10.1016/j.exger.2010.12.001. PMID 21167272.
Tardif, S; Ross, C; Bergman, P; Fernandez, E; Javors, M; Salmon, A; Spross, J; Strong, R; Richardson, A (19 July 2014). "Testing Efficacy of Administration of the Antiaging Drug Rapamycin in a Nonhuman Primate, the Common Marmoset". J Gerontol A Biol Sci Med Sci. 70 (5): 577–88. doi:10.1093/gerona/glu101. PMC 4400395. PMID 25038772.
Callaway, Ewen (2010). "Telomerase reverses ageing process". Nature. doi:10.1038/news.2010.635.
Blagosklonny, M.V. (2009). "Validation of anti-aging drugs by treating age-related diseases". Aging. 1 (3): 281–88. doi:10.18632/aging.100034. PMC 2806014. PMID 20157517.
Kogan, Valeria; Molodtcov, Ivan; Menshikov, Leonid I.; Shmookler Reis, Robert J.; Fedichev, Peter (2015). "Stability analysis of a model gene network links aging, stress resistance, and negligible senescence". Scientific Reports. 5: 13589. arXiv:1408.0463. Bibcode:2015NatSR...513589K. doi:10.1038/srep13589. PMC 4551969. PMID 26316217.
"Scientists' Open Letter on Aging" Archived 29 April 2015 at the Wayback Machine. imminst.org.
Miller, Richard A.; Harrison, David E.; Astle, Clinton M.; Floyd, Robert A.; Flurkey, Kevin; Hensley, Kenneth L.; Javors, Martin A.; Leeuwenburgh, Christiaan; Nelson, James F.; Ongini, Ennio; Nadon, Nancy L.; Warner, Huber R.; Strong, Randy (2007). "An aging Interventions Testing Program: Study design and interim report". Aging Cell. 6 (4): 565–75. doi:10.1111/j.1474-9726.2007.00311.x. PMID 17578509.
"Ageing". Gero. Retrieved 4 February 2015.
"Science for Life Extension". Science against aging foundation. Archived from the original on 18 February 2015. Retrieved 3 February 2015.
"FAQ – Palo Alto Longevity Prize". Palo Alto Longevity Prize. Retrieved 1 October 2014.
Ashlee Vance (9 September 2014). "Silicon Valley Investor Backs $1 Million Prize to End Death". Bloomberg Businessweek. Retrieved 1 October 2014.
"$1 Million Longevity Prize Seeks To "Hack The Aging Code"" (Press release). Yahoo! Finance. 9 September 2014. Archived from the original on 6 October 2014. Retrieved 1 October 2014.
Aaron Kinney (14 September 2014). "Silicon Valley launches another bid to 'hack' aging, cheat death". San Jose Mercury News. Retrieved 1 October 2014.
Victoria Thorp (23 November 2014). "The Palo Alto Prize: A 'Moonshot' at Increasing Longevity". Palo Alto Pulse. Retrieved 8 December 2014.
Phillips, Judith, Kristine Ajrouch, and Sarah Hillcoat-Nallétamby (2010) Key Concepts in Social Gerontology. SAGE Publications. ISBN 978-1-4462-0428-3. pp. 12–13.
Levy, Becca R.; Slade, Martin D.; Chang, E.-Shien; Kannoth, Sneha; Wang, Shi-Yi (2018). "Ageism Amplifies Cost and Prevalence of Health Conditions". The Gerontologist. doi:10.1093/geront/gny131. PMID 30423119.
"Ageing in the Twenty-First Century". UNFPA. 2012.
LO, W. (2015). The music culture of older adults in Cantonese operatic singing lessons. Ageing and Society, 35(8), 1614–34. doi:10.1017/S0144686X14000439
Vincent, John A. (2005). "Understanding generations: Political economy and culture in an ageing society". The British Journal of Sociology. 56 (4): 579–99. doi:10.1111/j.1468-4446.2005.00084.x. PMID 16309437.
"opulation Ageing and Development". UNFPA. 2002.
"Ageing". unfpa.org. UNFPA – United Nations Population Fund.
"UN Human Development Report 2005" (PDF). United Nations Development Programme. Archived from the original (PDF) on 27 May 2008. Retrieved 7 October 2010.
Chosewood, L. Casey. "Safer and Healthier at Any Age: Strategies for an Aging Workforce". NIOSH Science Blog. National Institute for Occupational Safety and Health. Retrieved 6 August 2012.
Basakha M; Yavari K; Sadeghi H; Naseri A. (2015). "Population Aging And Iran's Non-Oil Economic Growth". Payavard Salamat. 9 (2): 131–46.
Basakha M, Yavari K, Sadeghi H, Naseri A (2014). "Ageing and Macroeconomics; Healthcare cost disease as a threat to Iranian ageing society". Journal of Research in Health Sciences. 14 (2): 152–56. PMID 24728752.
Scheid, Teresa L.; Brown, Tony N. (2010). A Handbook for the Study of Mental Health (Second ed.). New York: Cambridge University Press.
Cullati, Stéphane; Kliegel, Matthias; Widmer, Eric (2018). "Development of reserves over the life course and onset of vulnerability in later life". Nature Human Behaviour. 2 (8): 551–58. doi:10.1038/s41562-018-0395-3. ISSN 2397-3374.
Panek, Paul E.; Hayslip, Bert (1989). Adult development and aging. San Francisco: Harper & Row. ISBN 978-0-06-045012-0.[page needed]
Anita Wejbrandt (2014) Defining aging in cyborgs: A bio-techno-social definition of aging, Journal of Aging Studies, Volume 31, pp. 104–09
Emmanuel EJ (October 2014). "Why I hope to die at 75: An argument that society and families – and you – will be better off if nature takes its course swiftly and promptly". The Atlantic. Retrieved 7 April 2015.
Faria MA. "Bioethics and why I hope to live beyond age 75 attaining wisdom!: A rebuttal to Dr. Ezekiel Emanuel′s 75 age limit". Surg Neurol Int 2015;6:35. Retrieved 7 April 2015.
Faria MA. "Longevity and compression of morbidity from a neuroscience perspective: Do we have a duty to die by a certain age?". Surg Neurol Int 2015;6:49. Retrieved 7 April 2015.
Chawla, Mukesh; Dubois, Hans F.W.; Chawla, Richard B. (2006). "The Impact of Aging on Long-Term Care in Europe and Some Potential Policy Responses". International Journal of Health Services. 36 (4): 719–46. doi:10.2190/AUL1-4LAM-4VNB-3YH0. PMID 17175843.
Reinhardt, U. E. (2003). "Does the Aging of the Population Really Drive the Demand for Health Care?". Health Affairs. 22 (6): 27–39. doi:10.1377/hlthaff.22.6.27. PMID 14649430.
Meara, E.; White, C.; Cutler, D. M. (2004). "Trends in Medical Spending by Age, 1963–2000". Health Affairs. 23 (4): 176–83. doi:10.1377/hlthaff.23.4.176. PMID 15318578.
Idler, E.L. (2003). "Discussion: Gender Differences in Self-Rated Health, in Mortality, and in the Relationship Between the Two". The Gerontologist. 43 (3): 372–75. doi:10.1093/geront/43.3.372.
Deeg, D. J. H.; Bath, P. A. (2003). "Self-Rated Health, Gender, and Mortality in Older Persons: Introduction to a Special Section". The Gerontologist. 43 (3): 369–71. doi:10.1093/geront/43.3.369. PMID 12810900.
Benyamini, Y.; Blumstein, T.; Lusky, A.; Modan, B. (2003). "Gender Differences in the Self-Rated Health-Mortality Association: Is It Poor Self-Rated Health That Predicts Mortality or Excellent Self-Rated Health That Predicts Survival?". The Gerontologist. 43 (3): 396–405, discussion 372–75. doi:10.1093/geront/43.3.396. PMID 12810904.
Kunzmann, Ute; Little, Todd D; Smith, Jacqui (2000). "Is age-related stability of subjective well-being a paradox? Cross-sectional and longitudional evidence from the Berlin Aging Study". Psychology and Aging. 15 (3): 511–26. doi:10.1037/0882-7974.15.3.511. PMID 11014714.
Jylhä, Marja; Guralnik, Jack M; Balfour, Jennifer; Fried, Linda P (2001). "Walking Difficulty, Walking Speed, and Age as Predictors of Self-Rated Health: The Women's Health and Aging Study". Journal of Gerontology. 56A (10): M609–17. PMID 11584033.
Heckhausen, Jutta (1999). Developmental Regulation in Adulthood: Age-Normative and Sociostructural Constraints as Adaptive Challenges. Cambridge University Press. ISBN 978-0-521-02713-7.
Sargent-Cox, Kerry; Anstey, Kaarin; Luszcz, Mary (2008). "Determinants of Self-Rated Health Items With Different Points of Reference". Journal of Aging and Health. 20 (6): 739–61. doi:10.1177/0898264308321035. PMID 18625760.
Idler, Ellen L (1993). "Age differences in self-assessments of health: Age changes, cohort difference, or survivorship?". Journal of Gerontology. 48 (6): S289. doi:10.1093/geronj/48.6.s289.
Williamson, JD; Fried, LP (1996). "Characterization of older adults who attribute functional decrements to "old age"". Journal of the American Geriatrics Society. 44 (12): 1429–34. doi:10.1111/j.1532-5415.1996.tb04066.x. PMID 8951311.
Baltes, Paul B.; Baltes, Margret M. (1990). "Psychological perspectives on successful aging: The model of selective optimization with compensation". In Baltes, Paul B.; Baltes, Margret M. (eds.). Successful Aging. pp. 1–34. doi:10.1017/CBO9780511665684.003. ISBN 978-0-511-66568-4.
Rowe, J.; Kahn, R. (1987). "Human aging: Usual and successful". Science. 237 (4811): 143–49. Bibcode:1987Sci...237..143R. doi:10.1126/science.3299702. PMID 3299702.
Job 14:5–7 A man’s days are numbered. You know the number of his months. He cannot live longer than the time You have set. So now look away from him that he may rest, until he has lived the time set for him like a man paid to work. For there is hope for a tree, when it is cut down, that it will grow again, and that its branches will not stop growing